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anti cx40 polyclonal antibody  (Thermo Fisher)


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    Structured Review

    Thermo Fisher anti cx40 polyclonal antibody
    Connexins expression and apoptosis level in a representative tissue sample from each type of patient: permanent AF, POAF and non-AF. <t>Cx40:</t> connexin 40; Cx43: connexin 43. Connexins can be seen in brown between the junctions of the cells. Apoptosis occurs when the nuclei of cardiomyocytes appear brown.
    Anti Cx40 Polyclonal Antibody, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 95/100, based on 129 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti cx40 polyclonal antibody/product/Thermo Fisher
    Average 95 stars, based on 129 article reviews
    anti cx40 polyclonal antibody - by Bioz Stars, 2026-03
    95/100 stars

    Images

    1) Product Images from "Endothelial activation, cell-cell interactions, and inflammatory pathways in postoperative atrial fibrillation following cardiac surgery"

    Article Title: Endothelial activation, cell-cell interactions, and inflammatory pathways in postoperative atrial fibrillation following cardiac surgery

    Journal: Biomedical Journal

    doi: 10.1016/j.bj.2024.100821

    Connexins expression and apoptosis level in a representative tissue sample from each type of patient: permanent AF, POAF and non-AF. Cx40: connexin 40; Cx43: connexin 43. Connexins can be seen in brown between the junctions of the cells. Apoptosis occurs when the nuclei of cardiomyocytes appear brown.
    Figure Legend Snippet: Connexins expression and apoptosis level in a representative tissue sample from each type of patient: permanent AF, POAF and non-AF. Cx40: connexin 40; Cx43: connexin 43. Connexins can be seen in brown between the junctions of the cells. Apoptosis occurs when the nuclei of cardiomyocytes appear brown.

    Techniques Used: Expressing

    Connexin levels. A. Cx40. B. Cx43. ∗ p < 0.05 ∗∗ p < 0.01 ∗∗∗ p < 0.001.
    Figure Legend Snippet: Connexin levels. A. Cx40. B. Cx43. ∗ p < 0.05 ∗∗ p < 0.01 ∗∗∗ p < 0.001.

    Techniques Used:



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    Fig. 3 | Acute structural and electrical functional analysis of CM-AI purified hiPSC-CM monolayers. a Western blot analysis of atrial-specific CM proteins in purified versus unpurified monolayers. CM-AI + Laser purified monolayers (n = 6, Lanes 1–6) showed significant enrichment of <t>Cx40,</t> cTnI, and mlc2a protein expression compared to time and batch-matched non-purified monolayers. b Cx40 protein expression was significantly enriched in laser-purified hiPSC-CM mono- layers compared to non-purified monolayers (0.73 ± 0.13au; n = 6 vs. 0.08 ± 0.01au; n = 3; ****P < 0.0001, unpaired t-test). c cTnI protein expression was significantly greater in laser-purified monolayers compared to non-purified hiPSC-CM atrial monolayers (0.31 ± 0.09au; n = 6 vs. 0.02 ± 0.01au; n = 3; ***P = 0.0009, unpaired t- test). d mlc2a myofilament protein expression was significantly enriched in laser- purified hiPSC-CM monolayers compared to non-purified monolayers (0.16 ± 0.08au; n = 6 vs. 0.03 ± 0.01; n = 3; *P = 0.04, unpaired t-test). e Atrial hiPSC-
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    Image Search Results


    Connexins expression and apoptosis level in a representative tissue sample from each type of patient: permanent AF, POAF and non-AF. Cx40: connexin 40; Cx43: connexin 43. Connexins can be seen in brown between the junctions of the cells. Apoptosis occurs when the nuclei of cardiomyocytes appear brown.

    Journal: Biomedical Journal

    Article Title: Endothelial activation, cell-cell interactions, and inflammatory pathways in postoperative atrial fibrillation following cardiac surgery

    doi: 10.1016/j.bj.2024.100821

    Figure Lengend Snippet: Connexins expression and apoptosis level in a representative tissue sample from each type of patient: permanent AF, POAF and non-AF. Cx40: connexin 40; Cx43: connexin 43. Connexins can be seen in brown between the junctions of the cells. Apoptosis occurs when the nuclei of cardiomyocytes appear brown.

    Article Snippet: After endogenous peroxidase and unspecific background blocking, sections were incubated with the corresponding primary antibody diluted in blocking solution overnight at 4 °C (anti-Cx40 polyclonal Antibody [36–4900, Invitrogen, dilution 1/100] and anti-Cx43 monoclonal Antibody [13–8300, Invitrogen, dilution 1/250]).

    Techniques: Expressing

    Connexin levels. A. Cx40. B. Cx43. ∗ p < 0.05 ∗∗ p < 0.01 ∗∗∗ p < 0.001.

    Journal: Biomedical Journal

    Article Title: Endothelial activation, cell-cell interactions, and inflammatory pathways in postoperative atrial fibrillation following cardiac surgery

    doi: 10.1016/j.bj.2024.100821

    Figure Lengend Snippet: Connexin levels. A. Cx40. B. Cx43. ∗ p < 0.05 ∗∗ p < 0.01 ∗∗∗ p < 0.001.

    Article Snippet: After endogenous peroxidase and unspecific background blocking, sections were incubated with the corresponding primary antibody diluted in blocking solution overnight at 4 °C (anti-Cx40 polyclonal Antibody [36–4900, Invitrogen, dilution 1/100] and anti-Cx43 monoclonal Antibody [13–8300, Invitrogen, dilution 1/250]).

    Techniques:

    Fig. 3 | Acute structural and electrical functional analysis of CM-AI purified hiPSC-CM monolayers. a Western blot analysis of atrial-specific CM proteins in purified versus unpurified monolayers. CM-AI + Laser purified monolayers (n = 6, Lanes 1–6) showed significant enrichment of Cx40, cTnI, and mlc2a protein expression compared to time and batch-matched non-purified monolayers. b Cx40 protein expression was significantly enriched in laser-purified hiPSC-CM mono- layers compared to non-purified monolayers (0.73 ± 0.13au; n = 6 vs. 0.08 ± 0.01au; n = 3; ****P < 0.0001, unpaired t-test). c cTnI protein expression was significantly greater in laser-purified monolayers compared to non-purified hiPSC-CM atrial monolayers (0.31 ± 0.09au; n = 6 vs. 0.02 ± 0.01au; n = 3; ***P = 0.0009, unpaired t- test). d mlc2a myofilament protein expression was significantly enriched in laser- purified hiPSC-CM monolayers compared to non-purified monolayers (0.16 ± 0.08au; n = 6 vs. 0.03 ± 0.01; n = 3; *P = 0.04, unpaired t-test). e Atrial hiPSC-

    Journal: Communications biology

    Article Title: AI-guided laser purification of human iPSC-derived cardiomyocytes for next-generation cardiac cell manufacturing.

    doi: 10.1038/s42003-025-08162-0

    Figure Lengend Snippet: Fig. 3 | Acute structural and electrical functional analysis of CM-AI purified hiPSC-CM monolayers. a Western blot analysis of atrial-specific CM proteins in purified versus unpurified monolayers. CM-AI + Laser purified monolayers (n = 6, Lanes 1–6) showed significant enrichment of Cx40, cTnI, and mlc2a protein expression compared to time and batch-matched non-purified monolayers. b Cx40 protein expression was significantly enriched in laser-purified hiPSC-CM mono- layers compared to non-purified monolayers (0.73 ± 0.13au; n = 6 vs. 0.08 ± 0.01au; n = 3; ****P < 0.0001, unpaired t-test). c cTnI protein expression was significantly greater in laser-purified monolayers compared to non-purified hiPSC-CM atrial monolayers (0.31 ± 0.09au; n = 6 vs. 0.02 ± 0.01au; n = 3; ***P = 0.0009, unpaired t- test). d mlc2a myofilament protein expression was significantly enriched in laser- purified hiPSC-CM monolayers compared to non-purified monolayers (0.16 ± 0.08au; n = 6 vs. 0.03 ± 0.01; n = 3; *P = 0.04, unpaired t-test). e Atrial hiPSC-

    Article Snippet: Primary antibodies used include: Cx40 (ThermoFisher; Cat #36-4900), cTnI (Abcam; ab47003), and mlc2a (Synaptic Systems; #311011).

    Techniques: Functional Assay, Western Blot, Expressing